Harmony: Fetal DNA in maternal blood

harmony is a non-invasive prenatal test performed with a simple blood sample that can detect trisomy 13, 18 and 21, sex chromosome abnormalities and fetal sex.

harmony allows for a significant reduction of the need for invasive procedures such as amniocentesis and chorionic villus biopsy, which can cause miscarriage in about 0.5 to 1% of cases.

In case of a positive harmony test result (high risk for trisomy), an invasive diagnostic technique will be suggested to confirm this result.

When: From 10 weeks

Time frame: 5 to 11 working days

Inclusions: Fetal sex + Sex chromosome anomalies

Advantage: Fetal DNA test approved by Health Canada

Detection rate for trisomy 21: over 99.9%.

Induced hyperglycemia – Gestational diabetes test

Also known as gestational diabetes, hyperglycemia is a condition defined by an increase in blood sugar, most commonly during the second trimester of pregnancy. In most cases, gestational diabetes disappears after childbirth. However, in some cases, the mother could develop type 2 diabetes in the following years.

The cause of gestational diabetes is the result of hormonal changes experienced during pregnancy: hormones in the placenta interfere with the action of the pancreas. It cannot secrete enough insulin, which leads to hyperglycemia.

Without insulin, a hormone that nourishes our cells which is naturally secreted by the pancreas, glucose will accumulate in the bloodstream and cause hyperglycemia.

adhesioRT

adhesioRT is an endometrial receptivity test that complements conventional assisted reproduction techniques. This test allows a personalized embryo transfer by identifying the precise moment when the endometrium is receptive. It is thus possible to synchronize the dialogue between the embryo and the endometrium, and increase the potential for pregnancy. The adhesioRT test is a key complement to conventional assisted reproduction techniques by optimizing the chances of embryo implantation following transfer.

The Alessio DNA fragmentation test

The Alessio sperm DNA fragmentation test uses fluorescent biomarkers to measure the proportion of sperm with fragmented DNA. The quality of the genetic information carried by the sperm is a determining factor in the development of a viable embryo. Sperm DNA fragmentation corresponds to “breaks” in the sperm’s genetic material that cannot be detected by conventional examinations. A high number of breaks reduces the chances that a pregnancy will be carried to term, and could be the cause of certain fertility problems.

Extended Carrier Genetic Testing (customizable, up to 289 genes)

Carrier genetic testing can identify your genetic status (carrier or non-carrier) for so-called recessive and X-linked conditions, and reduce the risk of transmission to your future children. It may be recommended if there is a consanguinity link between you and your partner, if your family history is not well known or simply if you wish to have more reassurance to reduce your genetic risks in a preconception context.

Procedure for performing a genetic analysis:

• If you already have a detailed prescription, contact the fertility department to schedule a sample*.
• If you would like a genetic consultation beforehand to evaluate your needs, send your detailed medical prescription to: genetique@cliniqueovo.com

Delays in obtaining genetic analysis results: maximum 21 days

*The prescribing physician is responsible for interpreting the results.

Serological analysis COVID-19-SARS-CoV-2 IgG

The SARS-CoV-2 IgG assay is intended for the detection of antibodies to SARS-CoV-2 in serum and plasma from individuals suspected of having had coronavirus (COVID-19)