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Harmony : Fetal DNA in maternal blood

Recent development have allowed for a new type of screening test: cell free fetal DNA in maternal blood. This new generation of tests isolates the fetus’s DNA (genetic material) directly circulating in the mother’s blood. DNA is then analyzed in the laboratory providing the most accurate screening profile currently available.

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    clinique ovo montreal

    All services offered 8000, boul. Décarie,
    Montreal Qc H4P 2S4
    ovo fertility office 100 & 200
    Monday to Friday 7:30am to 6:00pm
    Weekend on appointment
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    ovo cryo Monday to Wed. 8:00am to 5:00pm
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    Thursday 9:00am to 4:00pm
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    ovo biosurance office 600
    Monday to Friday 8:00am to 4:00pm
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    ovo labo office 600
    Monday to Friday 8:00am to 4:00pm
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    ovo prenatal office 600
    Monday to Friday 8:00am to 4:00pm
    prenatal@cliniqueovo.com
    ovo r&d office 600
    Monday to Friday 7:15am to 5:00pm
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    clinique ovo rive-sud

    3141, boul. Taschereau,
    Greenfield Park Qc J4V 2H2
    ovo fertility - certain services offered office 410
    Call to know our hours
    fertilite@cliniqueovo.com
    ovo prenatal - certain services offered office 420
    Monday to Friday 8:00am to 4:00pm
    prenatal@cliniqueovo.com
    ovo labo - certain services offered office 420
    Monday to Friday 8:00am to 4:00pm
    labo@cliniqueovo.com

    clinique ovo quebec

    ovo prenatal - certain services offered 2600 Boul. Laurier, suite 295,
    Quebec Qc G1V 4T3
    Monday to Friday 8:00am to 4:00pm prenatal@cliniqueovo.com



    clinique ovo rive-nord

    ovo prenatal - Prenatal screening 1000 Montée des Pionniers,
    Terrebonne QC J6V 1S8
    Monday to Thursday 9:00am to 3:00pm
    prenatal@cliniqueovo.com
    Montreal and South-Shore: t. 514.798.2000
    Quebec: t. 418.425.0128
    f. 514.798.2001

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harmony™ is a non-invasive prenatal screening test which allows for the risk assessment of trisomies 21, 18 and 13 as well as the screening of sex chromosome abnormalities in the fetus. Harmony is performed on a maternal blood sample as of the 10th week of pregnancy. Screening tests for sex chromosome abnormalities and the determination of fetal sex is available upon written request from your attending physician. harmony detection rate for trisomies 21, 18 and 13 is over 99% and at 92% for sex chromosome abnormalities.

 

If the results of the harmony™ test are positive (high risk of a trisomy), an invasive diagnostic test will be recommended to confirm the results.

The harmony™ test is done on a simple maternal blood sample as early as the tenth week of pregnancy. Available in five business days, the results will indicate the risk (low or high) of the fetus having one of the conditions screened for by the test. If the risk is high, your doctor will continue to follow you and may recommend that you undergo prenatal diagnostic testing. The results of a fetal DNA test on maternal blood alone are not sufficient grounds for a medical abortion. For patients presenting with a high risk of one of the conditions screened for by the harmony™ test, a FISH test on the amniotic fluid will be offered free of charge further to an amniocentesis. In a small proportion of cases (< 4%), the test results will be inconclusive. This does not mean that the fetus has or does not have the condition, but rather that the test results were not accurate enough to determine the risk level, or that not enough of your baby’s DNA was detectable in your blood.

 

The harmony™ test is offered to patients with single or twin pregnancies, having had fertility treatments with or without donor sperm or eggs. The test cannot be done before the tenth week of pregnancy. The patient is responsible for ensuring the gestational age and progress of the pregnancy, as well as the number of fetuses, before proceeding with the test. Therefore, it is recommended that she have an ultrasound before undergoing the harmony™ test.

 

If the Fetal DNA test Harmony fails to show a result, a partial refund will be offered.

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