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Prenatal diagnostic

A prenatal diagnostic test accurately determines the presence or absence of chromosomal abnormalities, such as trisomies. Prenatal diagnostic tests involve invasive techniques (chorionic villus sampling or amniocentesis), thus presenting a risk to the pregnancy.

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    clinique ovo montreal

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    8000, boul. Décarie,
    Montreal Qc H4P 2S4

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    3141, boul. Taschereau,
    Greenfield Park Qc J4V 2H2

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    ovo prenatal – certain services offered
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    Quebec Qc G1V 4T3

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    ovo prenatal – Prenatal screening
    1000 Montée des Pionniers,
    Terrebonne QC J6V 1S8

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    clinique Echo-medic

    Ovo prenatal – certain services

    Laval
    1575, boul. de l’Avenir, suite 110,
    Laval Qc H7S 2N5
    t. 1.877.664.3246
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    Boisbriand
    20865, chemin de la Côte Nord, suite 201
    Boisbriand Qc J7E 4H5
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    Montreal and South-Shore: t. 514.798.2000
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Amniocentesis or Chorionic biopsy

Amniocentesis involves collecting a sample of amniotic fluid using a needle. It is done under ultrasound guidance as of the 15th week of pregnancy; the risk of spontaneous abortion (miscarriage) is approximately 1/200.

 

Chorionic villus sampling (CVS) involves collecting chorionic villi from the placenta using a needle. It is done under ultrasound guidance between the 11th and 14th weeks of pregnancy. CVS is more risky than amniocentesis with an approximately 1/100 risk of spontaneous abortion (miscarriage). It is performed under special circumstances only.

 

Prenatal diagnostic tests are performed on a doctor’s request. The material collected during a prenatal diagnostic test (amniotic fluid or chorionic villi) is then analyzed in a laboratory.

 

 

CONVENTIONAL ANALYSIS

The conventional prenatal diagnostic test, called karyotyping, consists of observing the number and structure of chromosomes in the fetus’s DNA. It provides highly accurate results (99.9% detection rate) for many chromosomal abnormalities, including trisomies. The results of this conventional test are available in two weeks. This test is automatically done on all amniocentesis or CVS samples.

FISH ANALYSIS

The FISH test provides preliminary results for some of the most common chromosomal abnormalities, for example, trisomies 13, 18 and 21, and sex chromosome (X and Y) abnormalities. Results are available in 48 hours. The detection rate with this test is 98%. In the event the FISH test shows a chromosomal abnormality, the results of the conventional karyotyping test are needed before making a final decision about the pregnancy. A pregnancy cannot be terminated based solely on the result of the FISH test. This optional test is done on an amniocentesis or CVS sample.